例2 : Read the passage and then listen to the recording. Read the integrated writing question and the five responses that follow. Evaluate each response according to the descriptions of the five levels. Assign each response a score of 5,4,3,2 or 1. Reading Time – 3 minutes The discovery of penicillin and other antibiotic drugs is the most dramatic medical development of the twentieth century. These new drugs quickly became known as “wonder drugs” because they saved so many lives that were threatened by major forms of infection. The research that led to their development rested on the belief that chemicals could be found that would destroy specific microorganisms without injuring the human body at the same time. Advances in chemistry and in the knowledge of bacteria quickened the discovery of such chemicals. In 1933, the first of the sulfa drugs, prontosil, was tested clinically on humans and was found to cure blood infections that would otherwise have been fatal. In 1941, the first successful human tests of penicillin were conducted on cases of streptococcus infections. The discovery of penicillin laid the foundation for even more powerful weapons against specific diseases. Within the next decade, researchers identified some 200 antibiotic substances that were effective against one or another type of bacteria. One of the most important was streptomycin, found to be potent against tuberculosis and other infections that were not affected by penicillin. Antibiotics gave the medical profession powerful tools that could directly fight a very wide range of specific diseases. They made possible the survival of patients during and after surgery. No longer was it necessary to depend largely on the body’s own immune system to fight off major infections; these infections could be attacked directly with drugs. Among the most spectacular effects of antibiotics were reductions in the number of deaths from pneumonia and tuberculosis. Now listen to part of a lecture in a biology class. As soon as we developed antibiotics, new strains of bacteria appeared that were resistant to some or all of the drugs. Hospitals started using antibiotics regularly in the 1950s, but resistance started appearing within a few years. Today, one-third of the patients in hospitals are on antibiotics, but antibiotic resistance is increasing the danger of hospital infections—to the point where people are almost safer staying home than going to a hospital. In the forties, penicillin really was a wonder drug. Back then, you could give a patient with bacterial pneumonia ten thousand units of penicillin four times a day and cure the disease. Today, you could give 24 million units of penicillin a day, but the patient might still die. Why? Well, in a way, bacteria are smarter than us. They evolve to counteract any drug we attack them with. A lot of bacteria are now completely resistant to penicillin. Bacteria can evolve very effective weapons against antibiotics. Some of them develop enzymes to match every antibiotic we throw at them. All these weapons and counter-weapons match one another—just like the weapons in real military warfare. So, no matter what antibiotic we use, the bacteria will come up with a way to make it useless. How does this happen? Well, if you douse a colony of bacteria with an antibiotic the colony will be killed—that is, all except for a few cells. A few cells will survive because they carry a resistance gene for that particular antibiotic. The surviving cells quickly multiply and they pass along this lucky gene to their offspring. And soon you have a new strain of bacteria that’s resistant to that drug. One consequence of antibiotic resistance is the reappearance of tuberculosis as a major illness. Twenty years ago, doctors thought tuberculosis was a defeated disease. Since then, however, new cases of tuberculosis have increased by 20 percent. And several strains of the disease are resistant to any drug we can attack them with. Summarize the main points made in the lecture, explaining how they differ from points made in the reading.
Summarize the main points made in the lecture, explaining how they differ from points made in the reading.
Response A Score:_____ The lecture discusses the resistance of bacteria to antibiotics, which differs from the main idea in the reading that antibiotics are “wonder drugs.” When antibiotics were developed in the 1940s, they were successful in curing many diseases. However, bacteria quickly became resistant to some drugs. Today, many people in hospital take antibiotics, but there is the serious danger of hospital infections. Penicillin used to cure diseases such as pneumonia, but today people might still die because bacteria are resistant to the drug. Bacteria develop resistance to antibiotics because they evolve weapons against the drugs. They can evolve strategies to fight any drug we give them. This situation is similar to the weapons of two armies use in a war. When you treat a disease with an antibiotic, it will kill the bacteria. However, a few cells will survive. Soon the new type of bacteria will appear, and resistant to the antibiotic. Therefore, we should not consider antibiotics as wonder drugs because the bacteria also have strong weapons. One result of antibiotic resistance is the increase in new cases of tuberculosis. Doctors used to believe that antibiotics were powerful weapons against diseases such as tuberculosis. However, today several types are resistant to antibiotics, so it is a new and serious problem. This is another reason why antibiotics are not wonder drugs. Response B Score:_____ I will describe how the resistance of bacteria to antibiotics. First, it’s big problem in the hospitals. Hospitals used antibiotics in 1950, but resistance appearing a problem. The reason is danger of hospital infection is very bad so people had better stay home a hospital. Second, penicillin was a wonder drug in 1940. You gave a man in hospital 10000 penicillin and he cured the disease. But today you give 24 penicillin but he might die. The reason is bacteria smart so very difficult treat pneumonia and other disease in a hospital. Several people die – because the reason is the resistance of the bacteria to antibiotics. Third, how does this happen is you dose a colony of bacteria with an antibiotic. The colony killed except a few cells. This is a dangerous problem in a hospital because people may die. Doctors think tuberculosis was a defeated disease but the increase is by 20%. The changes the view of antibiotics as ‘wonder drugs’ by resistance of bacteria to antibiotics. It’s a big problem today and doctors can’t find drugs to cure the disease such as tuberculoses. Penicillin and other antibiotic drugs were wonder drugs in 1940-so it’s necessary to have a different view of antibiotics today. Response C Score:_____ I discuss a biology professor talk about antibiotics. These new drugs as wonder drugs saving many people who very sick the diseases. Professor he describe penicillin as wonder drug it causing many people well after sick. The discovery of penicillin and other antibiotic drugs is the most dramatic medical development of the twentieth century quickly become known as ‘wonder drugs. ‘Antibiotics gave the medical profession powerful tools that could fight a very wide range of specific diseases. Professor he gave example the antibiotics make the survival of patients. For example, blood infections, pneumonia and tuberculosis. As a result, reductions in the number of death. Response D Score:_____ In general, the lecture contradicts the idea that antibiotics are “wonder drugs” as the reading states. On the contrary, antibiotics are not wonder drugs because the resistance of bacteria to antibiotics. According to the reading, the discovery of penicillin and other antibiotic drugs saved many lives that were threatened by dangerous diseases such a pneumonia and tuberculosis. In the twentieth century, penicillin was first a wonder drug because it can cure streptococcus infections. Furthermore, streptomycin found to be potent against tuberculosis. However, the lecture made the point that this is not true in the present. Today tuberculosis is a major illness again because the new strain of bacteria is resistant to antibiotics. According to the lecture, bacteria have developed effective weapons against some drugs, for example, penicillin. They evolve to counteract antibiotics. It happens when a few cells of bacteria survive because they have the resistance gene. Then new strains of bacteria appeared. After that, antibiotics may attack but they do not kill all disease infections. This serious problem today is the resistance of bacteria to antibiotics. In the past, antibiotic drugs could attack and kill diseases, but this is not true today. Therefore, it is necessary to develop new wonder drugs to fight disease. Response E Score:_____ The resistance of bacteria to antibiotics changes the view of wonder drugs. One example is penicillin. It is wonder drug in 1941, when the first successful human tests of penicillin. The discovery of penicillin the foundation for even more powerful drugs, for example, antibiotics. Another example is streptomycin, found against tuberculosis and other infections that were not affected by penicillin. The resistance of bacteria to antibiotics to some of the drugs. First example is pneumonia. In the past penicillin cure him, however today he still die. Second example is tuberculosis. The most effects of antibiotics were reductions in the number of deaths, however, since tuberculosis increase 20 percent deaths. It describes the resistance of bacteria to antibiotics. In the past, it was no problem, however, today it is serious problem. It’s changes the view of antibiotics as wonder drugs which saved so many lives. Because today people can still die.
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